Author: Dr. Geny Augustine Chasse
The supplement market is highly saturated, both in type of products and ingredients being used. It is ever-evolving, with bigger claims boasting tremendous results. With the KTA workout, the ingredient profile remains simple, yet effective. The focus is on the science behind each carefully chosen ingredient, boiling down to efficacy and maximizing bioavailability in the body.
How exactly does that translate into an ideal pre-workout composition? Efficacy is the ability of a substance to produce a desired result. When thinking about an efficacious pre-work out, I would want one that gives me adequate energy to fuel my workout, nutritional support to promote the muscle building process in the body, and adequate nutritional delivery to the muscles that are working at their optimal level to give adequate performance.
Bioavailability refers to the resulting amount of an ingredient/element that is ACTUALLY available for the body to use…once going through the harsh environments of the stomach and liver metabolic processes. The greater the bioavailability, the more effective the ingredients are…and the bigger bang you get for your buck.
In this part 1 of 3, we will look at the first few key ingredients which make the KTA pre-workout your best match for your hardcore workout regimes:
- L-Citrulline Malate
A. L-Citrulline Malate @ 2:1
Citrulline Malate brings us back to Biochemistry 101 with the Krebs Cycle and the Urea cycle. Both pathways may seem daunting, however are regularly happening processes in the body. The Urea cycle involves the conversion of the harmful waste product ammonia into urea, an excreatable product in our urine via the kidneys. What is not so straightforward is the benefit of citrulline in assisting in waste product excretion in the bodybuilding process; with increased energy demands and increased work being done by our various muscle groups, more nutritional demand is put on our body and resulting in the creation of larger amounts of waste products, particularly with protein metabolism. These waste products hinder peak performance, manifesting as cramping and fatigue and incomplete workouts. Citrulline is an intermediate in the urea cycle and therefore additional supplementation allows for the cycle to be accelerated, preventing acidity and toxic ammonia from accumulating in the body.
Another benefit of citrulline is its role in nitric oxide (NO) production and vasodilatory effects. Arginine is a widely- known precursor to nitric oxide. The problem with straight arginine supplementation is that it undergoes metabolism by liver enzymes, equaling decreased bioavailability and overall efficacy. Citrulline is the answer to this problem, as it bypasses the liver’s metabolic effect, allowing for a greater effective synthesis of NO and vasodilation- in other words… PUMP.
Recently there has been much intrigue and perhaps a question mark surrounding citrulline v.s. the composition of citrulline malate. Malate is an intermediate in the Krebs cycle, a process which takes place in our cell’s mitochondria- the ATP or “energy-producing” element. The ratio is in reference to the level of citrulline to malate. With 6g of citrulline malate, this translates to 4 g of citrulline and 2 g of malate per serving.
Malate supplementation allows for more malate to participate in this process, driving glucose and fatty acid metabolism at a higher level. This translates as increased RPM, and 1 rep max, supporting progression in your workouts.
The benefits don’t stop there as it has been discovered that citrulline’s conversion to arginine promotes greater growth hormone availability through its inhibitory effects on somatostatin the anti-GH hormone, which equals greater gains in muscle building.
AstraGin is a trademark ingredient which is used as a nutritional absorption booster. Again, the topic of increased bioavailability and efficacy come into play. Derived from the traditional Chinese medicinal plants; Panax notoginseng and Astragalus membrenaceus. Their active components participate in increased transport and availability via intestinal absorption of Tryptophan, arginine, glucose, folate, lysine, and histidine.
BioPerine is another trademark ingredient. BioPerine is commonly known as piperine- an ingredient derived from black pepper.
This ingredient is a promoter of increased metabolism, and fat burning. A greater metabolic demand on the body results in an increased demand for nutritional availability. The body responds appropriately, by increasing the mechanisms in which absorption takes place, ultimately causing greater efficiency in gut absorption of amino acids and vitamins alike.
Through the strategic combination of these athletic performance-enhancing ingredients, Peak Fit Labs has your fitness goals as our number one priority with straightforward, high-quality ingredients that are effective and result driven, always.
Stoppani, Jim. Supplement Breakdown: Citrulline v.s. Arginine. Retrieved from
Stoppani, Jim (August 6, 2013). Citrulline Malate. Retrieved from
Rodrigues, Joey (March 21, 2011). Heath Facts: Citrulline Malate. Retrieved from https://www.bodybuilding.com/fun/southfacts_cit.htm
Wang, Michael. AstraGin. Retrieved from https://nulivscience.com/astragin/.
Author Unknown. BioPerine: Product Write Up. Retrieved from http://www.restorativeformulations.com/site/restorativeformulations/library/Bioperine%20write%20up.pdf